Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p095 | (1) | WCRB2014

The effect of vitrification on subsequent mouse embryo development and postnatal health

Khalif Raja Ili Airina Raja , Smyth Neil , Fleming Tom , Velazquez Miguel Abraham , Sheth Bhav , Smith Stephanie

Short-term effects of cryopreservation on embryo development, survival and after embryo transfer (ET), resulting pregnancy rate have been documented. However, long-term effects on offspring remain relatively unexplored.Materials and methods: Using a mouse model, we investigated the effect of vitrification on blastocyst trophectoderm (TE) and inner cell mass (ICM) cell numbers by differential staining and postnatal growth and cardiovascular and metabolic ...

ra0002o008 | Oral Communications 1: Embryo and Implantation | SRF2015

The effect of IVF and embryo culture on mouse development and adult health

Aljahdali Anan , Raja Khalif Raja Ili Airina , Velazquez Miguel Abraham , Sheth Bhav , Smyth Neil , Fleming Tom

Several million babies have been born worldwide since IVF and assisted-reproductive technologies (ART) became available. However, reports link IVF techniques with adverse short- and long-term health outcomes.1,2,3 Using a mouse model, we investigated the effect of IVF on the total cell number in blastocyst stage embryos and the postnatal health of offspring.Methods: Experimental groups; (NM) C57/BL6 non-superovulated females naturally mated wi...